Información ORCID de CASTRO GONZALEZ, CARMEN
Biografía
adult brain neurogenesis
Educación
Doctora en Ciencias Biológicas (Bioquímica y Biología Molecular)
Universidad Autónoma de Madrid: Madrid, Madrid, España
20/02/1994 hasta 04/12/1998
Licenciada con Grado (Fisiología Animal II)
Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, España
01/09/1992 hasta 18/02/1994
Licenciada en Ciencias Biológicas
Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, España
30/09/1987 hasta 30/06/1992
Empleo
Profesora Titular de Universidad (Fisiología)
Universidad de Cadiz Ciencias de la Salud: Cadiz, Andalucía, España
28/07/2010
Profesora Contratada Doctora (Fisiologia)
Universidad de Cadiz: Cadiz, Andalucía, España
01/09/2009 hasta 28/07/2010
Contratada Ramón y Cajal (Fisiología)
Universidad de Cádiz: Cádiz, Andalucía, España
01/09/2004 hasta 31/08/2009
Postdoctoral Research Associate (Integrative Physiology)
University of Illinois at Urbana-Champaign: Urbana, IL, US
01/01/2000 hasta 31/08/2004
Becaria Posdoctoral (Hepatología y Terapia Génica)
Universidad de Navarra: Pamplona, Navarra, España
06/12/1998 hasta 31/12/1999
Becaria Predoctoral (Hepatología y Terapia Génica)
Universidad de Navarra: Pamplona, Navarra, España
01/02/1998 hasta 05/12/1998
Obras
New pharmacological tools: the use of diterpenes to promote adult hippocampal neurogenesis
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2024 | JOURNAL_ARTICLE
DOI: 10.4103/1673-5374.389635
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Targeting epidermal growth factor receptor signaling to facilitate cortical injury repair?
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2024 | JOURNAL_ARTICLE
DOI: 10.4103/1673-5374.385291
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Influence of High-Intensity Interval Training on Neuroplasticity Markers in Post-Stroke Patients: Systematic Review
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2024 | JOURNAL_ARTICLE
DOI: 10.3390/jcm13071985
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Migratory Response of Cells in Neurogenic Niches to Neuronal Death: The Onset of Harmonic Repair?
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2023 | JOURNAL_ARTICLE
DOI: 10.3390/ijms24076587
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Defining a Correlative Transcriptional Signature Associated with Bulk Histone H3 Acetylation Levels in Adult Glioblastomas
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2023 | JOURNAL_ARTICLE
DOI: 10.3390/cells12030374
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Targeting transforming growth factor alpha to recruit newly generated neuroblasts in cortical brain injuries
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2023 | OTHER
DOI: 10.21203/rs.3.rs-2277744/v1
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Polyphosphate Activates von Willebrand Factor Interaction with Glycoprotein Ib in the Absence of Factor VIII In Vitro
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2022 | JOURNAL_ARTICLE
DOI: 10.3390/ijms232214118
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Oxidative Stress as a Potential Mechanism Underlying Membrane Hyperexcitability in Neurodegenerative Diseases
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2022 | JOURNAL_ARTICLE
DOI: 10.3390/antiox11081511
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Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits
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2022 | JOURNAL_ARTICLE
DOI: 10.3390/ijms23105347
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Refinement of Active and Passive Membrane Properties of Layer V Pyramidal Neurons in Rat Primary Motor Cortex During Postnatal Development.
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2021 | JOURNAL_ARTICLE
DOI: 10.3389/fnmol.2021.754393
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Potential Diagnostic Value of the Differential Expression of Histone H3 Variants between Low- and High-Grade Gliomas.
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2021 | JOURNAL_ARTICLE
DOI: 10.3390/cancers13215261
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Phorbol Diesters and 12-Deoxy-16-hydroxyphorbol 13,16-Diesters Induce TGFα Release and Adult Mouse Neurogenesis.
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2021 | JOURNAL_ARTICLE
DOI: 10.1021/acs.jmedchem.1c00156
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Targeting Protein Kinase C in Glioblastoma Treatment.
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2021 | JOURNAL_ARTICLE
DOI: 10.3390/biomedicines9040381
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Age-Dependent Vulnerability to Oxidative Stress of Postnatal Rat Pyramidal Motor Cortex Neurons
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2020 | JOURNAL_ARTICLE
DOI: 10.3390/antiox9121307
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Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action
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2020 | JOURNAL_ARTICLE
DOI: 10.1038/s41386-020-00934-y
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Olfactory Neuroepithelium Cells from Cannabis Users Display Alterations to the Cytoskeleton and to Markers of Adhesion, Proliferation and Apoptosis
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2020 | JOURNAL_ARTICLE
DOI: 10.1007/s12035-020-02205-9
EID: 2-s2.0-85096616907
Parte de ISBN: 15591182 08937648
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Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments.
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2020 | JOURNAL_ARTICLE
DOI: 10.3389/fonc.2020.614295
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A novel PKC activating molecule promotes neuroblast differentiation and delivery of newborn neurons in brain injuries
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2020 | JOURNAL_ARTICLE
DOI: 10.1038/s41419-020-2453-9
EID: 2-s2.0-85083764382
Parte de ISBN: 20414889
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Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: A role for Wnt/β-catenin signaling
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2020 | JOURNAL_ARTICLE
DOI: 10.18632/aging.103510
EID: 2-s2.0-85088495694
Parte de ISBN: 19454589
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Lathyrane, Premyrsinane, and Related Diterpenes from Euphorbia boetica: Effect on in Vitro Neural Progenitor Cell Proliferation
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2019 | JOURNAL_ARTICLE
DOI: 10.1021/acs.jnatprod.9b00343
EID: 2-s2.0-85072716956
Parte de ISBN: 15206025 01633864
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ADAM17/TACE: a key molecule in brain injury regeneration.
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2019 | JOURNAL_ARTICLE
DOI: 10.4103/1673-5374.253517
EID: 2-s2.0-85063962630
Parte de ISBN: 18767958 16735374
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Protein Kinase C: Targets to Regenerate Brain Injuries?
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2019 | JOURNAL_ARTICLE
DOI: 10.3389/fcell.2019.00039
EID: 2-s2.0-85065313947
Parte de ISBN: 2296634X
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Protein Kinase C Inhibition Mediates Neuroblast Enrichment in Mechanical Brain Injuries.
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2018 | JOURNAL_ARTICLE
DOI: 10.3389/fncel.2018.00462
EID: 2-s2.0-85058927311
Parte de ISBN: 16625102
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Specific inhibition of ADAM17/TACE promotes neurogenesis in the injured motor cortex
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2018 | JOURNAL_ARTICLE
DOI: 10.1038/s41419-018-0913-2
EID: 2-s2.0-85052366651
Parte de ISBN: 20414889
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ELAC (3,12-di-O -acetyl-8-O -tigloilingol), a plant-derived lathyrane diterpene, induces subventricular zone neural progenitor cell proliferation through PKCβ activation
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2017 | JOURNAL_ARTICLE
DOI: 10.1111/bph.13846
EID: 2-s2.0-85020381667
Parte de ISBN: 14765381 00071188
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Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation.
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2016 | JOURNAL_ARTICLE
DOI: 10.1016/j.bbamcr.2016.09.018
EID: 2-s2.0-84989237146
Parte de ISBN: 18792596 01674889
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12-Deoxyphorbols Promote Adult Neurogenesis by Inducing Neural Progenitor Cell Proliferation via PKC Activation.
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2016 | JOURNAL_ARTICLE
DOI: 10.1093/ijnp/pyv085
EID: 2-s2.0-84964792106
Parte de ISBN: 14695111 14611457
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Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance
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2014 | JOURNAL_ARTICLE
DOI: 10.1002/hipo.22274
EID: 2-s2.0-84902550118
Parte de ISBN: 10981063 10509631
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Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of Psychosis: Toward an Integrative Inflammatory Hypothesis of Schizophrenia
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2014 | JOURNAL_ARTICLE
DOI: 10.1093/schbul/sbt001
EID: 2-s2.0-84895756733
Parte de ISBN: 17451701 05867614
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Diterpenes isolated from Euphorbia Sp that promote neurogenesis from neural stem cells
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2012 | JOURNAL_ARTICLE
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Inducing neural progenitor cells proliferation by the diterpene 3,12-di-O-acetyl-8-O-tigloylingol from Euphorbia lactea
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2012 | JOURNAL_ARTICLE
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Overexpression of Dyrk1a in neural progenitor cell cultures avoids the antiproliferative effect of Hcy
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2012 | JOURNAL_ARTICLE
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Plasma antioxidant capacity is reduced in Asperger syndrome
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2012 | JOURNAL_ARTICLE
DOI: 10.1016/j.jpsychires.2011.10.004
EID: 2-s2.0-84857140361
Parte de ISBN: 00223956 18791379
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ADAM-17/Tumor Necrosis Factor-alpha-Converting Enzyme Inhibits Neurogenesis and Promotes Gliogenesis from Neural Stem Cells
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2011 | JOURNAL_ARTICLE
DOI: 10.1002/stem.710
EID: 2-s2.0-80053267986
Parte de ISBN: 10665099
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OXIDATIVE STRESS IN FIRST-EPISODE EARLY-ONSET PSYCHOSES
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2011 | JOURNAL_ARTICLE
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S-Nitrosylation of the epidermal growth factor receptor: A regulatory mechanism of receptor tyrosine kinase activity
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2009 | JOURNAL_ARTICLE
DOI: 10.1016/j.freeradbiomed.2008.10.048
EID: 2-s2.0-58649088011
Parte de ISBN: 08915849
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Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase
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2008 | JOURNAL_ARTICLE
DOI: 10.1074/jbc.M710449200
EID: 2-s2.0-44049092351
Parte de ISBN: 1083351X 00219258
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Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression
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2008 | JOURNAL_ARTICLE
DOI: 10.1096/fj.08-109306
EID: 2-s2.0-55549117471
Parte de ISBN: 08926638
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Liver betaine-hornocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc
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2008 | JOURNAL_ARTICLE
DOI: 10.1016/j.abb.2008.01.017
EID: 2-s2.0-40649100255
Parte de ISBN: 00039861 10960384
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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells.
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2006 | JOURNAL_ARTICLE
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Assigning enzymatic function to betaine-homocysteine S-methyltransfearse-2 (BHMT2) as an S-methylmethionine (SMM)-specific homocysteine (Hcy) methyltransferase
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2006 | JOURNAL_ARTICLE
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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells
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2006 | JOURNAL_ARTICLE
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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells
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2006 | JOURNAL_ARTICLE
EID: 2-s2.0-33748773885
Parte de ISBN: 03906078
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Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis
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2004 | JOURNAL_ARTICLE
DOI: 10.1021/bi049821x
EID: 2-s2.0-2442603566
Parte de ISBN: 00062960
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Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency
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2004 | JOURNAL_ARTICLE
DOI: 10.1016/j.metabol.2003.10.033
EID: 2-s2.0-2342501877
Parte de ISBN: 00260495
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Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine: homocysteine S-methyltransferase.
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2003 | JOURNAL_ARTICLE
DOI: 10.1016/s1074-5521(03)00008-5
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Cloning and expression of the human choline dehydrogenase cDNA
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2003 | JOURNAL_ARTICLE
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Combining combinatorial chemistry and affinity chromatography: Highly selective inhibitors of human betaine - Homocysteine S-methyltransferase
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2003 | JOURNAL_ARTICLE
DOI: 10.1016/S1074-5521(03)00008-5
EID: 2-s2.0-0037330285
Parte de ISBN: 10745521
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Combining combinatorial chemistry and affinity chromatography: Highly selective inhibitors of human betaine: Homocysteine S-methyltransferase
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2003 | JOURNAL_ARTICLE
DOI: 10.1016/s1074-5521(03)0008-5
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Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency
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2003 | JOURNAL_ARTICLE
DOI: 10.1096/fj.02-0456fje
EID: 2-s2.0-0037364454
Parte de ISBN: 15306860
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Betaine-homocysteine methyltransferase: Zinc in a distorted barrel
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2002 | JOURNAL_ARTICLE
DOI: 10.1016/s0969-2126(02)00796-7
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Betaine-homocysteine methyltransferase: Zinc in a distorted barrel
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2002 | JOURNAL_ARTICLE
DOI: 10.1016/S0969-2126(02)00796-7
EID: 2-s2.0-0036711477
Parte de ISBN: 09692126
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Regulation of mammalian liver methionine adenosyltransferase
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2002 | JOURNAL_ARTICLE
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Regulation of mammalian liver methionine adenosyltransferase
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2002 | JOURNAL_ARTICLE
DOI: 10.1093/jn/132.8.2377s
EID: 2-s2.0-17544393875
Parte de ISBN: 00223166
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The use of intrinsic florescence (IF), circular dichroism (CD), initial rate kinetics and solvent viscosity to probe human betaine-homocysteine methyltransferase (BHMT) function
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2002 | JOURNAL_ARTICLE
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Betaine homocysteine methyltransferase (BHMT) transcription is inhibited by supplementing human hepatoma cell culture media with S-adenosylmethionine (AdoMet)
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2001 | JOURNAL_ARTICLE
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Expression and characterization of a novel betaine-homocysteine methyltransferase (BHMT)-like cDNA reveals new structure-function relations in the BHMT molecule
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2001 | JOURNAL_ARTICLE
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Redox regulation of betaine-homocysteine methyltransferase (BHMT) activity
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2001 | JOURNAL_ARTICLE
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Altered assembly of gap junction channels caused by COOH-terminal connexin32 mutants of CMTX
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1999 | BOOK_CHAPTER
DOI: 10.1111/j.1749-6632.1999.tb08628.x
EID: 2-s2.0-0033554319
Parte de ISBN: 00778923
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Altered formation of hemichannels and gap junction channels caused by C- terminal connexin-32 mutations
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1999 | JOURNAL_ARTICLE
DOI: 10.1523/jneurosci.19-10-03752.1999
EID: 2-s2.0-0344171987
Parte de ISBN: 02706474
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Altered formation of hemichannels and gap junction channels caused by C-terminal connexin-32 mutations
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1999 | JOURNAL_ARTICLE
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Creation of a functional S-nitrosylation site in vitro by single point mutation
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1999 | JOURNAL_ARTICLE
DOI: 10.1016/s0014-5793(99)01267-3
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Creation of a functional S-nitrosylation site in vitro by single point mutation
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1999 | JOURNAL_ARTICLE
DOI: 10.1016/S0014-5793(99)01267-3
EID: 2-s2.0-0032835199
Parte de ISBN: 00145793
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Methionine adenosyltransferase S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target thiol
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1999 | JOURNAL_ARTICLE
DOI: 10.1074/jbc.274.24.17075
EID: 2-s2.0-0038758127
Parte de ISBN: 00219258
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Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions
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1999 | JOURNAL_ARTICLE
DOI: 10.1016/s0006-3495(99)76986-9
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Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions
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1999 | JOURNAL_ARTICLE
DOI: 10.1016/S0006-3495(99)76986-9
EID: 2-s2.0-0032838486
Parte de ISBN: 00063495
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Assembly of chimeric connexin-aequorin proteins into functional gap junction channels - Reporting intracellular and plasma membrane calcium environments
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1998 | JOURNAL_ARTICLE
DOI: 10.1074/jbc.273.3.1719
EID: 2-s2.0-0031953118
Parte de ISBN: 00219258
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Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytes
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1997 | JOURNAL_ARTICLE
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Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytes
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1997 | JOURNAL_ARTICLE
DOI: 10.1016/S0006-3495(97)78108-6
EID: 2-s2.0-0030814751
Parte de ISBN: 00063495
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Progesterone does not alter sympathetic activity in tissues involved in energy balance
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1996 | JOURNAL_ARTICLE
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Progesterone does not alter sympathetic activity in tissues involved in energy balance
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1996 | JOURNAL_ARTICLE
DOI: 10.1530/eje.0.1340508
EID: 2-s2.0-15844415941
Parte de ISBN: 08044643
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REDUCED OXYGEN-CONSUMPTION OF BROWN ADIPOCYTES ISOLATED FROM PROGESTERONE-TREATED RATS
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1994 | JOURNAL_ARTICLE
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Reduced oxygen consumption of brown adipocytes isolated from progesterone-treated rats
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1994 | JOURNAL_ARTICLE
DOI: 10.1139/y94-174
EID: 2-s2.0-0028593476
Parte de ISBN: 00084212
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