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UniversidaddeCádiz
CTS562 Unidad de Neurobiología


Información ORCID de CASTRO GONZÁLEZ, CARMEN


Biografía


adult brain neurogenesis


Educación


Doctora en Ciencias Biológicas (Bioquímica y Biología Molecular)

Universidad Autónoma de Madrid: Madrid, Madrid, España

20/02/1994 hasta 04/12/1998


Licenciada con Grado (Fisiología Animal II)

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, España

01/09/1992 hasta 18/02/1994


Licenciada en Ciencias Biológicas

Universidad Complutense de Madrid: Madrid, Comunidad de Madrid, España

30/09/1987 hasta 30/06/1992



Empleo


Profesora Titular de Universidad (Fisiología)

Universidad de Cadiz Ciencias de la Salud: Cadiz, Andalucía, España

28/07/2010


Profesora Contratada Doctora (Fisiologia)

Universidad de Cadiz: Cadiz, Andalucía, España

01/09/2009 hasta 28/07/2010


Contratada Ramón y Cajal (Fisiología)

Universidad de Cádiz: Cádiz, Andalucía, España

01/09/2004 hasta 31/08/2009


Postdoctoral Research Associate (Integrative Physiology)

University of Illinois at Urbana-Champaign: Urbana, IL, US

01/01/2000 hasta 31/08/2004


Becaria Posdoctoral (Hepatología y Terapia Génica)

Universidad de Navarra: Pamplona, Navarra, España

06/12/1998 hasta 31/12/1999


Becaria Predoctoral (Hepatología y Terapia Génica)

Universidad de Navarra: Pamplona, Navarra, España

01/02/1998 hasta 05/12/1998



Obras


Acute Colon Inflammation Triggers Primary Motor Cortex Glial Activation, Neuroinflammation, Neuronal Hyperexcitability, and Motor Coordination Deficits

2022 | JOURNAL_ARTICLE

DOI: 10.3390/ijms23105347

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Refinement of Active and Passive Membrane Properties of Layer V Pyramidal Neurons in Rat Primary Motor Cortex During Postnatal Development.

2021 | JOURNAL_ARTICLE

DOI: 10.3389/fnmol.2021.754393

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Potential Diagnostic Value of the Differential Expression of Histone H3 Variants between Low- and High-Grade Gliomas.

2021 | JOURNAL_ARTICLE

DOI: 10.3390/cancers13215261

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Phorbol Diesters and 12-Deoxy-16-hydroxyphorbol 13,16-Diesters Induce TGFα Release and Adult Mouse Neurogenesis.

2021 | JOURNAL_ARTICLE

DOI: 10.1021/acs.jmedchem.1c00156

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Targeting Protein Kinase C in Glioblastoma Treatment.

2021 | JOURNAL_ARTICLE

DOI: 10.3390/biomedicines9040381

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Age-Dependent Vulnerability to Oxidative Stress of Postnatal Rat Pyramidal Motor Cortex Neurons

2020 | JOURNAL_ARTICLE

DOI: 10.3390/antiox9121307

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Effects of classical PKC activation on hippocampal neurogenesis and cognitive performance: mechanism of action

2020 | JOURNAL_ARTICLE

DOI: 10.1038/s41386-020-00934-y

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Olfactory Neuroepithelium Cells from Cannabis Users Display Alterations to the Cytoskeleton and to Markers of Adhesion, Proliferation and Apoptosis

2020 | JOURNAL_ARTICLE

DOI: 10.1007/s12035-020-02205-9

EID: 2-s2.0-85096616907

Parte de ISBN: 15591182 08937648

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Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments.

2020 | JOURNAL_ARTICLE

DOI: 10.3389/fonc.2020.614295

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A novel PKC activating molecule promotes neuroblast differentiation and delivery of newborn neurons in brain injuries

2020 | JOURNAL_ARTICLE

DOI: 10.1038/s41419-020-2453-9

EID: 2-s2.0-85083764382

Parte de ISBN: 20414889

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Vitamin D deficiency as a potential risk factor for accelerated aging, impaired hippocampal neurogenesis and cognitive decline: A role for Wnt/β-catenin signaling

2020 | JOURNAL_ARTICLE

DOI: 10.18632/aging.103510

EID: 2-s2.0-85088495694

Parte de ISBN: 19454589

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Lathyrane, Premyrsinane, and Related Diterpenes from Euphorbia boetica: Effect on in Vitro Neural Progenitor Cell Proliferation

2019 | JOURNAL_ARTICLE

DOI: 10.1021/acs.jnatprod.9b00343

EID: 2-s2.0-85072716956

Parte de ISBN: 15206025 01633864

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ADAM17/TACE: a key molecule in brain injury regeneration.

2019 | JOURNAL_ARTICLE

DOI: 10.4103/1673-5374.253517

EID: 2-s2.0-85063962630

Parte de ISBN: 18767958 16735374

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Protein Kinase C: Targets to Regenerate Brain Injuries?

2019 | JOURNAL_ARTICLE

DOI: 10.3389/fcell.2019.00039

EID: 2-s2.0-85065313947

Parte de ISBN: 2296634X

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Protein Kinase C Inhibition Mediates Neuroblast Enrichment in Mechanical Brain Injuries.

2018 | JOURNAL_ARTICLE

DOI: 10.3389/fncel.2018.00462

EID: 2-s2.0-85058927311

Parte de ISBN: 16625102

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Specific inhibition of ADAM17/TACE promotes neurogenesis in the injured motor cortex

2018 | JOURNAL_ARTICLE

DOI: 10.1038/s41419-018-0913-2

EID: 2-s2.0-85052366651

Parte de ISBN: 20414889

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ELAC (3,12-di-O -acetyl-8-O -tigloilingol), a plant-derived lathyrane diterpene, induces subventricular zone neural progenitor cell proliferation through PKCβ activation

2017 | JOURNAL_ARTICLE

DOI: 10.1111/bph.13846

EID: 2-s2.0-85020381667

Parte de ISBN: 14765381 00071188

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Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation.

2016 | JOURNAL_ARTICLE

DOI: 10.1016/j.bbamcr.2016.09.018

EID: 2-s2.0-84989237146

Parte de ISBN: 18792596 01674889

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12-Deoxyphorbols Promote Adult Neurogenesis by Inducing Neural Progenitor Cell Proliferation via PKC Activation.

2016 | JOURNAL_ARTICLE

DOI: 10.1093/ijnp/pyv085

EID: 2-s2.0-84964792106

Parte de ISBN: 14695111 14611457

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Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance

2014 | JOURNAL_ARTICLE

DOI: 10.1002/hipo.22274

EID: 2-s2.0-84902550118

Parte de ISBN: 10981063 10509631

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Pro-/Anti-inflammatory Dysregulation in Patients With First Episode of Psychosis: Toward an Integrative Inflammatory Hypothesis of Schizophrenia

2014 | JOURNAL_ARTICLE

DOI: 10.1093/schbul/sbt001

EID: 2-s2.0-84895756733

Parte de ISBN: 17451701 05867614

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Diterpenes isolated from Euphorbia Sp that promote neurogenesis from neural stem cells

2012 | JOURNAL_ARTICLE

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Inducing neural progenitor cells proliferation by the diterpene 3,12-di-O-acetyl-8-O-tigloylingol from Euphorbia lactea

2012 | JOURNAL_ARTICLE

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Overexpression of Dyrk1a in neural progenitor cell cultures avoids the antiproliferative effect of Hcy

2012 | JOURNAL_ARTICLE

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Plasma antioxidant capacity is reduced in Asperger syndrome

2012 | JOURNAL_ARTICLE

DOI: 10.1016/j.jpsychires.2011.10.004

EID: 2-s2.0-84857140361

Parte de ISBN: 00223956 18791379

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ADAM-17/Tumor Necrosis Factor-alpha-Converting Enzyme Inhibits Neurogenesis and Promotes Gliogenesis from Neural Stem Cells

2011 | JOURNAL_ARTICLE

DOI: 10.1002/stem.710

EID: 2-s2.0-80053267986

Parte de ISBN: 10665099

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OXIDATIVE STRESS IN FIRST-EPISODE EARLY-ONSET PSYCHOSES

2011 | JOURNAL_ARTICLE

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S-Nitrosylation of the epidermal growth factor receptor: A regulatory mechanism of receptor tyrosine kinase activity

2009 | JOURNAL_ARTICLE

DOI: 10.1016/j.freeradbiomed.2008.10.048

EID: 2-s2.0-58649088011

Parte de ISBN: 08915849

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Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase

2008 | JOURNAL_ARTICLE

DOI: 10.1074/jbc.M710449200

EID: 2-s2.0-44049092351

Parte de ISBN: 1083351X 00219258

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Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression

2008 | JOURNAL_ARTICLE

DOI: 10.1096/fj.08-109306

EID: 2-s2.0-55549117471

Parte de ISBN: 08926638

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Liver betaine-hornocysteine S-methyltransferase activity undergoes a redox switch at the active site zinc

2008 | JOURNAL_ARTICLE

DOI: 10.1016/j.abb.2008.01.017

EID: 2-s2.0-40649100255

Parte de ISBN: 00039861 10960384

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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells.

2006 | JOURNAL_ARTICLE

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Assigning enzymatic function to betaine-homocysteine S-methyltransfearse-2 (BHMT2) as an S-methylmethionine (SMM)-specific homocysteine (Hcy) methyltransferase

2006 | JOURNAL_ARTICLE

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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells

2006 | JOURNAL_ARTICLE

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Inorganic polyphosphate and specific induction of apoptosis in human plasma cells

2006 | JOURNAL_ARTICLE

EID: 2-s2.0-33748773885

Parte de ISBN: 03906078

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Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis

2004 | JOURNAL_ARTICLE

DOI: 10.1021/bi049821x

EID: 2-s2.0-2442603566

Parte de ISBN: 00062960

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Effects of betaine in a murine model of mild cystathionine-beta-synthase deficiency

2004 | JOURNAL_ARTICLE

DOI: 10.1016/j.metabol.2003.10.033

EID: 2-s2.0-2342501877

Parte de ISBN: 00260495

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Combining combinatorial chemistry and affinity chromatography: highly selective inhibitors of human betaine: homocysteine S-methyltransferase.

2003 | JOURNAL_ARTICLE

DOI: 10.1016/s1074-5521(03)00008-5

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Cloning and expression of the human choline dehydrogenase cDNA

2003 | JOURNAL_ARTICLE

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Combining combinatorial chemistry and affinity chromatography: Highly selective inhibitors of human betaine - Homocysteine S-methyltransferase

2003 | JOURNAL_ARTICLE

DOI: 10.1016/S1074-5521(03)00008-5

EID: 2-s2.0-0037330285

Parte de ISBN: 10745521

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Combining combinatorial chemistry and affinity chromatography: Highly selective inhibitors of human betaine: Homocysteine S-methyltransferase

2003 | JOURNAL_ARTICLE

DOI: 10.1016/s1074-5521(03)0008-5

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Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency

2003 | JOURNAL_ARTICLE

DOI: 10.1096/fj.02-0456fje

EID: 2-s2.0-0037364454

Parte de ISBN: 15306860

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Betaine-homocysteine methyltransferase: Zinc in a distorted barrel

2002 | JOURNAL_ARTICLE

DOI: 10.1016/s0969-2126(02)00796-7

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Betaine-homocysteine methyltransferase: Zinc in a distorted barrel

2002 | JOURNAL_ARTICLE

DOI: 10.1016/S0969-2126(02)00796-7

EID: 2-s2.0-0036711477

Parte de ISBN: 09692126

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Regulation of mammalian liver methionine adenosyltransferase

2002 | JOURNAL_ARTICLE

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Regulation of mammalian liver methionine adenosyltransferase

2002 | JOURNAL_ARTICLE

DOI: 10.1093/jn/132.8.2377s

EID: 2-s2.0-17544393875

Parte de ISBN: 00223166

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The use of intrinsic florescence (IF), circular dichroism (CD), initial rate kinetics and solvent viscosity to probe human betaine-homocysteine methyltransferase (BHMT) function

2002 | JOURNAL_ARTICLE

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Betaine homocysteine methyltransferase (BHMT) transcription is inhibited by supplementing human hepatoma cell culture media with S-adenosylmethionine (AdoMet)

2001 | JOURNAL_ARTICLE

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Expression and characterization of a novel betaine-homocysteine methyltransferase (BHMT)-like cDNA reveals new structure-function relations in the BHMT molecule

2001 | JOURNAL_ARTICLE

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Redox regulation of betaine-homocysteine methyltransferase (BHMT) activity

2001 | JOURNAL_ARTICLE

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Altered assembly of gap junction channels caused by COOH-terminal connexin32 mutants of CMTX

1999 | BOOK_CHAPTER

DOI: 10.1111/j.1749-6632.1999.tb08628.x

EID: 2-s2.0-0033554319

Parte de ISBN: 00778923

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Altered formation of hemichannels and gap junction channels caused by C- terminal connexin-32 mutations

1999 | JOURNAL_ARTICLE

DOI: 10.1523/jneurosci.19-10-03752.1999

EID: 2-s2.0-0344171987

Parte de ISBN: 02706474

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Altered formation of hemichannels and gap junction channels caused by C-terminal connexin-32 mutations

1999 | JOURNAL_ARTICLE

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Creation of a functional S-nitrosylation site in vitro by single point mutation

1999 | JOURNAL_ARTICLE

DOI: 10.1016/s0014-5793(99)01267-3

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Creation of a functional S-nitrosylation site in vitro by single point mutation

1999 | JOURNAL_ARTICLE

DOI: 10.1016/S0014-5793(99)01267-3

EID: 2-s2.0-0032835199

Parte de ISBN: 00145793

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Methionine adenosyltransferase S-nitrosylation is regulated by the basic and acidic amino acids surrounding the target thiol

1999 | JOURNAL_ARTICLE

DOI: 10.1074/jbc.274.24.17075

EID: 2-s2.0-0038758127

Parte de ISBN: 00219258

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Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions

1999 | JOURNAL_ARTICLE

DOI: 10.1016/s0006-3495(99)76986-9

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Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions

1999 | JOURNAL_ARTICLE

DOI: 10.1016/S0006-3495(99)76986-9

EID: 2-s2.0-0032838486

Parte de ISBN: 00063495

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Assembly of chimeric connexin-aequorin proteins into functional gap junction channels - Reporting intracellular and plasma membrane calcium environments

1998 | JOURNAL_ARTICLE

DOI: 10.1074/jbc.273.3.1719

EID: 2-s2.0-0031953118

Parte de ISBN: 00219258

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Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytes

1997 | JOURNAL_ARTICLE

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Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytes

1997 | JOURNAL_ARTICLE

DOI: 10.1016/S0006-3495(97)78108-6

EID: 2-s2.0-0030814751

Parte de ISBN: 00063495

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Progesterone does not alter sympathetic activity in tissues involved in energy balance

1996 | JOURNAL_ARTICLE

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Progesterone does not alter sympathetic activity in tissues involved in energy balance

1996 | JOURNAL_ARTICLE

DOI: 10.1530/eje.0.1340508

EID: 2-s2.0-15844415941

Parte de ISBN: 08044643

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REDUCED OXYGEN-CONSUMPTION OF BROWN ADIPOCYTES ISOLATED FROM PROGESTERONE-TREATED RATS

1994 | JOURNAL_ARTICLE

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Reduced oxygen consumption of brown adipocytes isolated from progesterone-treated rats

1994 | JOURNAL_ARTICLE

DOI: 10.1139/y94-174

EID: 2-s2.0-0028593476

Parte de ISBN: 00084212

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